2025 Volume No 50 – pages 124-136
Title: An analysis of predictive factors and potential mechanisms underlying lumbar disc herniation resorption |
Authors: L You, ZY Xiao, Y Yang, L Pei, HS Jing, GQ Chen |
Address: Acupuncture and Rehabilitation Department, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, 646000 Luzhou, Sichuan, China |
E-mail: chenguiquan1973 at 126.com |
Abstract: Spontaneous resorption of lumbar disc herniation (RLDH) is a frequently observed phenomenon in imaging studies. However, the predictors of this process are difficult to control, posing a major clinical challenge. Moreover, the underlying biological mechanisms of RLDH remain incompletely understood. This limitation hinders clinicians from optimizing non-surgical treatments of lumbar disc herniation (LDH) in clinical practice. This review summarized the existing literature on the resorption of LDH, aiming to elucidate the predictive factors and potential biomechanical processes underlying this disease. Additionally, existing therapeutic approaches designed to promote resorption were also summarized. By providing insights into the dynamics of LDH resorption, this review offers the possibility of enhancing diagnostic accuracy and facilitating the development of targeted treatment strategies. |
Keywords: Lumbar disc herniation, resorption, mechanisms, predictive factors, macrophages. |
Publication date: 24th April 2025 |
Copyright policy: © 2025 The Author(s). Published by Forum Multimedia Publishing, LLC. This article is distributed in accordance with Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/4.0/). |
Article download: Pages 124-136 (PDF file) |
